DNA Translocation Through Graphene Nanopores

DNA translocation through graphene nanopores.

We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter. Due to the thin nature of the graphene membranes, we observe larger blocked currents than for traditional solid-state nanopores. However, ionic current noise levels are several orders of magnitude l...

DNA translocation through graphene nanopores.

Nanopores--nanosized holes that can transport ions and molecules--are very promising devices for genomic screening, in particular DNA sequencing. Solid-state nanopores currently suffer from the drawback, however, that the channel constituting the pore is long, approximately 100 times the distance between two bases in a DNA molecule (0.5 nm for single-stranded DNA). This paper provides proof of ...

Supporting Information DNA Translocation Through Graphene Nanopores

We have plotted and fitted the data both as R(d) and as G(d) = 1/R(d), which will have the effect of emphasizing the weight of data points at small and large diameters, respectively. We fitted a variety of fitting functions to these data, as indicated in Figure S1. Table S1 displays the resulting fitting parameters as well as the χ 2 value, the reduced sum of the squared residuals. From a compa...

Simulations of DNA translocation through nanopores

DNA translocation through low-noise glass nanopores.

The effect of electron irradiation-induced shrinking on glass nanocapillaries with diameters ranging from 75 to 14 nm was analyzed by measuring the conductance characteristics with and without DNA translocation. We have investigated nanocapillary shrinking with a scanning electron microscope from several perspectives to understand the geometry of the shrunken nanocapillary. On the basis of this...